5-Amino-1MQ (Capsules)
NNMT Inhibitor
CAS: 42464-96-0
Formula: C10H12N2
M.W.: 160.2192 g/mol
Purity: 99%+ HPLC Verified
Ref No.: 5-A-0050TA
For Research Use Only (RUO)
Not for human or veterinary use.
5-Amino-1MQ (Capsules)
Category
GLP / Metabolic Research
CAS Number
42464-96-0
Form Factor
Capsules
In stock, ready to ship
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Products are shipped in capsule form.
5-Amino-1MQ is a small-molecule NNMT inhibitor investigated in experimental models of cellular energy metabolism and adipose-tissue regulation. Research examines its effects on NNMT activity, NAD+ homeostasis, metabolic pathway utilization, energy expenditure, and adipose-tissue endpoints independent of feeding-behavior changes.
Description
5-Amino-1MQ is a small-molecule NNMT inhibitor investigated in experimental models of cellular energy metabolism and adipose-tissue regulation. Research examines its effects on NNMT activity, NAD+ homeostasis, metabolic pathway utilization, energy expenditure, and adipose-tissue endpoints independent of feeding-behavior changes.Chemical Information
CAS Number
42464-96-0
Purity
99%+ HPLC Verified
Molecular Formula
C10H12N2
Molar Mass
160.2192 g/mol
Form Factor
Capsules
Synonyms
Research Applications
- Metabolic Research: 5-Amino-1MQ is studied as a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). Research examines how NNMT inhibition increases NAD+ levels, activates sirtuin longevity pathways, and shifts cellular metabolism from energy storage toward energy expenditure.
- Adipose Tissue Biology Research: 5-Amino-1MQ is studied for its ability to reprogram adipose tissue metabolism through NAD+ salvage pathway activation. Research demonstrates reduced adipocyte lipid accumulation and increased basal metabolic rate without feeding-behavior changes.
- Epigenetics Research: 5-Amino-1MQ is studied for its effects on methylation pathway dynamics. By inhibiting NNMT, it alters the balance of S-adenosylmethionine (SAM) and nicotinamide metabolism, affecting DNA methylation patterns and histone modifications.
- Pharmacology Research: 5-Amino-1MQ serves as a lead compound in NNMT inhibitor drug development. Research profiles its selectivity for NNMT over other methyltransferases and establishes structure-activity relationships.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for 5-Amino-1MQ (Capsules) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
5-Amino-1MQ is a small-molecule NNMT inhibitor investigated in experimental models of cellular energy metabolism and adipose-tissue regulation. Research examines its effects on NNMT activity, NAD+ homeostasis, metabolic pathway utilization, energy expenditure, and adipose-tissue endpoints independent of feeding-behavior changes.Chemical Information
CAS Number
42464-96-0
Purity
99%+ HPLC Verified
Molecular Formula
C10H12N2
Molar Mass
160.2192 g/mol
Form Factor
Capsules
Synonyms
Research Applications
- Metabolic Research: 5-Amino-1MQ is studied as a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). Research examines how NNMT inhibition increases NAD+ levels, activates sirtuin longevity pathways, and shifts cellular metabolism from energy storage toward energy expenditure.
- Adipose Tissue Biology Research: 5-Amino-1MQ is studied for its ability to reprogram adipose tissue metabolism through NAD+ salvage pathway activation. Research demonstrates reduced adipocyte lipid accumulation and increased basal metabolic rate without feeding-behavior changes.
- Epigenetics Research: 5-Amino-1MQ is studied for its effects on methylation pathway dynamics. By inhibiting NNMT, it alters the balance of S-adenosylmethionine (SAM) and nicotinamide metabolism, affecting DNA methylation patterns and histone modifications.
- Pharmacology Research: 5-Amino-1MQ serves as a lead compound in NNMT inhibitor drug development. Research profiles its selectivity for NNMT over other methyltransferases and establishes structure-activity relationships.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for 5-Amino-1MQ (Capsules) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
