Ipamorelin
Selective Growth Hormone Secretagogue
CAS: 170851-70-4
Formula: C38H49N9O5
M.W.: 711.8531 g/mol
Purity: 99%+ HPLC Verified
Ref No.:IPA-0005VI
Ref No.:IPA-0010VI
For Research Use Only (RUO)
Not for human or veterinary use.
Ipamorelin
Category
GH / Neuro / Misc
CAS Number
170851-70-4
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in freeze dried powder form.
Ipamorelin is a pentapeptide growth hormone secretagogue with remarkable selectivity — it produces robust GH release with minimal impact on cortisol, prolactin, ACTH, or appetite, making it the cleanest GH secretagogue in its class while preserving natural pulsatile GH secretion patterns.
Description
Ipamorelin is a pentapeptide growth hormone secretagogue with remarkable selectivity — it produces robust GH release with minimal impact on cortisol, prolactin, ACTH, or appetite, making it the cleanest GH secretagogue in its class while preserving natural pulsatile GH secretion patterns.Chemical Information
CAS Number
170851-70-4
Secondary CAS
1622358-30-2
Purity
99%+ HPLC Verified
Molecular Formula
C38H49N9O5
Molar Mass
711.8531 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Endocrinology: Ipamorelin is studied as the most selective growth hormone secretagogue in its class. Unlike other GHRP-class peptides, it produces robust GH release with minimal effects on cortisol, prolactin, ACTH, or appetite. Research examines the molecular basis for this selectivity, including receptor binding affinity profiling and downstream signaling pathway analysis across different pituitary cell types.
- Bone Biology: Ipamorelin is actively studied in bone biology for its effects on osteoblast activity, bone mineral density, and skeletal turnover markers. Research demonstrates enhanced bone formation without the cortisol elevation that can promote bone resorption, positioning it as a GH secretagogue with favorable bone safety profiles. Studies examine long-term skeletal outcomes in osteoporosis and fracture healing models.
- Gerontology: In aging research, Ipamorelin is studied for addressing age-related GH decline with minimal systemic side effects. Its selectivity means it avoids the appetite stimulation (unlike GHRP-6), cortisol elevation (unlike GHRP-2), and prolactin increase seen with other GH secretagogues. Research examines whether this clean profile translates to better long-term tolerability in chronic aging intervention studies.
- Comparative Pharmacology: Ipamorelin is used as a reference compound in comparative GHRP selectivity studies. Research profiles its receptor binding, signaling cascade activation, and physiological effects against GHRP-2, GHRP-6, Hexarelin, and MK-677 to understand the structural determinants of GH secretagogue selectivity and develop next-generation compounds with optimized activity profiles.
Reconstitution Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for Ipamorelin — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
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Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Stacking Considerations
Ipamorelin is a selective GH secretagogue (GHRP) commonly combined with GHRH peptides for amplified GH release.
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