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BPC-157

Category

Healing / Growth / Cosmetic

CAS Number

137525-51-0

Form Factor

Lyophilized Powder

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BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It is one of the most studied peptides in tissue repair research, with over 100 preclinical studies demonstrating effects on GI protection, tendon healing, bone repair, and neuroprotection.

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It is one of the most studied peptides in tissue repair research, with over 100 preclinical studies demonstrating effects on GI protection, tendon healing, bone repair, and neuroprotection.

CAS Number

137525-51-0

Secondary CAS

1356647-49-2

Purity

99%+ HPLC Verified

Molecular Formula

C62H98N16O22

Molar Mass

1419.5347 g/mol

Form Factor

Lyophilized Powder

Synonyms

Body Protection Compound-157 Pentadecapeptide BPC 157 PL 14736
  • Gastroenterology: BPC-157 is extensively studied in gastroenterology for its cytoprotective effects on the gastrointestinal mucosa. Preclinical models demonstrate accelerated healing of gastric ulcers, protection against NSAID-induced mucosal damage, and restoration of intestinal barrier integrity. Research has shown it modulates the nitric oxide system, prostaglandin pathways, and dopamine/serotonin turnover within the gut, making it a key compound in inflammatory bowel disease and functional GI disorder research.
  • Orthopedic Medicine: In musculoskeletal research, BPC-157 has demonstrated remarkable effects on tendon, ligament, muscle, and bone healing in multiple animal models. Studies show accelerated Achilles tendon repair, enhanced quadriceps muscle healing, and improved bone fracture consolidation. The peptide appears to promote fibroblast outgrowth, increase growth factor expression (EGF, VEGF), and stimulate the formation of reticulin and collagen fibers at injury sites.
  • Neuroscience: BPC-157 has shown significant neuroprotective properties across dopaminergic, serotonergic, and GABAergic systems. Research models demonstrate protection against cuprizone-induced demyelination, recovery from traumatic brain injury, and restoration of dopamine system function following neurotoxic damage. It appears to modulate key neurotransmitter pathways and promote nerve regeneration, positioning it as a compound of interest in neurodegenerative disease and peripheral nerve injury research.
  • Wound Healing: BPC-157's angiogenic properties make it a focal compound in wound healing research. It promotes new blood vessel formation through VEGF upregulation, accelerates granulation tissue formation, and enhances collagen deposition at wound sites. Studies in diabetic and corticosteroid-impaired healing models show it can rescue compromised repair processes, making it relevant to chronic wound and surgical recovery research.
  • Toxicology: BPC-157 demonstrates broad cytoprotective effects against various toxic insults including NSAID-induced GI damage, alcohol-induced liver injury, and organ damage from potassium overdose. Its protective mechanisms involve modulation of the nitric oxide system, maintenance of vascular integrity, and stabilization of cellular membranes, making it a valuable tool in toxicological protection and organ preservation studies.

Reconstitution Protocol

  1. 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
  2. 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
  3. 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall β€” do not spray directly onto the powder.
  4. 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
  5. 5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20Β°C to 4Β°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8Β°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25Β°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) β€” not for human or veterinary use.

Quality Assurance Standards

Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.

Certificate of Analysis

Latest COA for BPC-157 β€” independently tested via HPLC and Mass Spectrometry.

Testing Methodology

Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.

  • β€’ HPLC β€” High-Performance Liquid Chromatography confirms peptide purity β‰₯98%.
  • β€’ Mass Spectrometry β€” Validates molecular identity and correct sequence.
  • β€’ Endotoxin (LAL) β€” Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
  • β€’ Sterility β€” Microbial contamination testing per USP standards.

Learn More About Peptides

Explore our research library covering purity, synthesis, storage, solubility, and more.

Peptide Information

Research Database

Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.

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    Synergistic tissue repair & angiogenesis

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Note: BPC-157 + TB-500 is one of the most well-studied synergistic peptide combinations.

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