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PT-141 (Spray)

Category

GH / Neuro / Misc Research

CAS Number

189691-06-3

Form Factor

Nasal Spray

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Selank Nasal Spray delivers the anxiolytic and nootropic peptide Selank intranasally, a delivery method validated in Russian clinical research. The nasal route provides direct CNS access via olfactory nerve pathways, preserving its dual anxiolytic-immunomodulatory profile with rapid onset and convenience.

Selank Nasal Spray delivers the anxiolytic and nootropic peptide Selank intranasally, a delivery method validated in Russian clinical research. The nasal route provides direct CNS access via olfactory nerve pathways, preserving its dual anxiolytic-immunomodulatory profile with rapid onset and convenience.

CAS Number

189691-06-3

Purity

99%+ HPLC Verified

Molecular Formula

C50H68N14O10

Molar Mass

1025.1781 g/mol

Form Factor

Nasal Spray

Synonyms

Bremelanotide (Nasal)
  • Intranasal Drug Delivery: PT-141 nasal spray is studied for the pharmacokinetics of melanocortin agonist delivery via the nasal mucosa. The intranasal route was used in early clinical development before transitioning to subcutaneous injection. Research examines nasal absorption efficiency, systemic bioavailability, and the time-to-onset of central effects compared to subcutaneous administration.
  • Sexual Medicine: Nasal PT-141 is investigated for non-invasive arousal signaling research. Studies examine whether intranasal delivery provides sufficient CNS melanocortin receptor activation to produce meaningful sexual function effects, and whether the convenience of nasal administration improves research compliance in chronic sexual dysfunction study protocols.
  • Pharmaceutical Sciences: PT-141 nasal spray formulation research examines optimal delivery parameters for a CNS-active peptide. Studies investigate spray volume, droplet size distribution, pH optimization, and preservative systems to maximize nasal bioavailability while maintaining formulation stability and patient acceptability in clinical research settings.

Reconstitution Protocol

  1. 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
  2. 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
  3. 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
  4. 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
  5. 5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) — not for human or veterinary use.

Quality Assurance Standards

Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.

Certificate of Analysis

Latest COA for PT-141 (Spray) — independently tested via HPLC and Mass Spectrometry.

Testing Methodology

Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.

  • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
  • Mass Spectrometry — Validates molecular identity and correct sequence.
  • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
  • Sterility — Microbial contamination testing per USP standards.

Learn More About Peptides

Explore our research library covering purity, synthesis, storage, solubility, and more.

Peptide Information

Research Database

Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.

View Research

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