GHK-Cu

Copper Tripeptide

CAS: 89030-95-5

Formula: C₁₄H₂₂CuN₆O₄

M.W.: 401.9105 g/mol

Purity: 99%+ HPLC Verified

Ref No.: GHK-0050VI

For Research Use Only (RUO)

Not for human or veterinary use.

COA Included With Every Order

Third-Party Lab Tested

Cold-Chain Packaging Included

Quality Guaranteed

Free Shipping on Orders $150+

99%+ HPLC Verified Purity

GHK-Cu

Name: GHK-Cu
SKU: ghk-cu
Availability: InStock

Category

Healing / Growth / Cosmetic

CAS Number

49557-75-7

Form Factor

Lyophilized Powder

Select mg:

50 mg

Clear

BUNDLE & SAVE

Quantity:

FREE Shipping on orders $150+ (after any discounts)

In stock, ready to ship

Ships same day before 12pm PST

Products are shipped in freeze dried powder form.

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding tripeptide first identified in human plasma in 1973. Its levels decline with age, correlating with diminished regenerative capacity. Genomic studies show it modulates over 4,000 human genes spanning collagen synthesis, antioxidant defense, and stem cell recruitment.

CAS Number

89030-95-5

Purity

99%+ HPLC Verified

Molecular Formula

C₁₄H₂₂CuN₆O₄

Molar Mass

401.9105 g/mol

Form Factor

Lyophilized Powder

Synonyms

Copper Tripeptide-1 Glycyl-L-Histidyl-L-Lysine Copper

Dermatology: GHK-Cu is one of the most extensively studied peptides in dermatological research, with over four decades of investigation into skin aging, wound healing, and scar remodeling. Studies demonstrate stimulation of collagen I, III, and V synthesis, increased elastin production, glycosaminoglycan accumulation, and enhanced fibroblast proliferation. Clinical studies confirm improvements in skin thickness, density, elasticity, and overall photoaging scores.
Genomics: GHK-Cu has been the subject of landmark genomic studies revealing it modulates the expression of over 4,000 human genes — approximately one-third of the human genome. Gene Ontology analysis shows it upregulates genes associated with tissue repair, antioxidant defense, and stem cell function while suppressing genes linked to inflammation, fibrosis, and tissue destruction. This broad genomic influence makes it a model compound for gene-regulatory peptide research.
Regenerative Medicine: In regenerative research, GHK-Cu is studied for its ability to recruit mesenchymal stem cells, activate tissue remodeling pathways, and reset gene expression patterns toward a healthier, more youthful phenotype. Research examines its effects on dermal, vascular, neural, and connective tissue regeneration, with implications for chronic wound management and age-related tissue deterioration.
Cosmetic Science: GHK-Cu is a leading active ingredient in cosmetic science research for anti-aging formulation development. Studies compare topical, injectable, and systemic delivery methods for optimal skin rejuvenation outcomes. Research examines its synergistic effects with other anti-aging compounds and its ability to improve skin hydration, firmness, and clarity across different age groups and skin types.
Oncology: Emerging oncological research examines GHK-Cu's ability to reset gene expression patterns in damaged cells toward a healthier phenotype. Studies investigate whether its broad genomic influence can suppress pro-metastatic gene networks, reduce cancer-associated inflammation, and modulate the tumor microenvironment. This represents a novel gene-regulatory approach to cancer prevention research.

Reconstitution Protocol

1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

Wear nitrile gloves and safety goggles when handling research compounds.
Work in a clean, controlled environment (laminar flow hood recommended).
Dispose of sharps and used materials in approved biohazard containers.
This product is for laboratory research use only (RUO) — not for human or veterinary use.

Quality Assurance Standards

Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.

Certificate of Analysis

Latest COA for GHK-Cu — independently tested via HPLC and Mass Spectrometry.

COA-GHKCU-06-2025

Testing Methodology

Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.

• HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
• Mass Spectrometry — Validates molecular identity and correct sequence.
• Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
• Sterility — Microbial contamination testing per USP standards.