NAD+ (Spray)
Nicotinamide Adenine Dinucleotide (Nasal)
CAS: 53-84-9
Formula: C21H28N7O14P2
M.W.: 664.4242 g/mol
Purity: 99%+ HPLC Verified
Ref No.: NAD-1500SP
For Research Use Only (RUO)
Not for human or veterinary use.
NAD+ (Spray)
Category
GH / Neuro / Misc Research
CAS Number
53-84-9
Form Factor
Nasal Spray
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in nasal spray form.
NAD+ Nasal Spray delivers Nicotinamide Adenine Dinucleotide intranasally for rapid cellular uptake and enhanced bioavailability compared to oral supplementation. It supports sirtuin activation, DNA repair, mitochondrial function, and neuroprotection against age-related cognitive decline via the nose-to-brain transport pathway.
Description
NAD+ Nasal Spray delivers Nicotinamide Adenine Dinucleotide intranasally for rapid cellular uptake and enhanced bioavailability compared to oral supplementation. It supports sirtuin activation, DNA repair, mitochondrial function, and neuroprotection against age-related cognitive decline via the nose-to-brain transport pathway.Chemical Information
CAS Number
53-84-9
Purity
99%+ HPLC Verified
Molecular Formula
C21H28N7O14P2
Molar Mass
664.4242 g/mol
Form Factor
Nasal Spray
Synonyms
Research Applications
- Longevity Science: NAD+ nasal spray is studied for intranasal delivery of this critical coenzyme for sirtuin activation and anti-aging research. The nasal route offers enhanced bioavailability compared to oral supplementation by bypassing GI degradation and hepatic first-pass metabolism. Research examines the kinetics of nasal NAD+ absorption, systemic distribution, and the correlation between plasma NAD+ elevation and sirtuin-dependent gene expression changes.
- Neuroscience: NAD+ spray is studied for nose-to-brain coenzyme delivery and neuroprotective applications. Research examines whether intranasal NAD+ reaches CNS targets in sufficient concentrations to support neuronal NAD+-dependent enzymes (sirtuins, PARPs, CD38), enhance mitochondrial function in brain tissue, and protect against age-related cognitive decline through direct CNS NAD+ repletion.
- Pharmaceutical Sciences: NAD+ nasal spray is studied for coenzyme bioavailability optimization via intranasal delivery. Research examines spray formulation parameters (pH, tonicity, viscosity), NAD+ stability in aqueous nasal formulations, the effect of mucosal absorption enhancers, and comparative bioavailability against oral, sublingual, and intravenous NAD+ delivery routes.
- Gerontology: NAD+ spray is studied for non-invasive NAD+ repletion in aging intervention research. Research examines whether intranasal delivery can achieve therapeutically relevant NAD+ elevation in elderly subjects, restore age-related NAD+ decline, and produce measurable improvements in mitochondrial function, DNA repair capacity, and sirtuin-mediated longevity pathway activation.
Laboratory Preparation Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved and the solution appears clear, as shown in the vial image.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
You May Also Like
Popular peptides you may also be interested in.
-
$124.99
Semax (Spray)
GH / Neuro / Misc Research View DetailsThis product has multiple variants. The options may be chosen on the product page -
$109.99
BPC-157 (Spray)
Tissue Repair / Regenerative Research View DetailsThis product has multiple variants. The options may be chosen on the product page -
$124.99
Selank (Spray)
GH / Neuro / Misc Research View DetailsThis product has multiple variants. The options may be chosen on the product page -
$109.99
PT-141 (Spray)
GH / Neuro / Misc Research View DetailsThis product has multiple variants. The options may be chosen on the product page
Popular Product
Popular Product
Popular Product
Popular Product
Description
NAD+ Nasal Spray delivers Nicotinamide Adenine Dinucleotide intranasally for rapid cellular uptake and enhanced bioavailability compared to oral supplementation. It supports sirtuin activation, DNA repair, mitochondrial function, and neuroprotection against age-related cognitive decline via the nose-to-brain transport pathway.Chemical Information
CAS Number
53-84-9
Purity
99%+ HPLC Verified
Molecular Formula
C21H28N7O14P2
Molar Mass
664.4242 g/mol
Form Factor
Nasal Spray
Synonyms
Research Applications
- Longevity Science: NAD+ nasal spray is studied for intranasal delivery of this critical coenzyme for sirtuin activation and anti-aging research. The nasal route offers enhanced bioavailability compared to oral supplementation by bypassing GI degradation and hepatic first-pass metabolism. Research examines the kinetics of nasal NAD+ absorption, systemic distribution, and the correlation between plasma NAD+ elevation and sirtuin-dependent gene expression changes.
- Neuroscience: NAD+ spray is studied for nose-to-brain coenzyme delivery and neuroprotective applications. Research examines whether intranasal NAD+ reaches CNS targets in sufficient concentrations to support neuronal NAD+-dependent enzymes (sirtuins, PARPs, CD38), enhance mitochondrial function in brain tissue, and protect against age-related cognitive decline through direct CNS NAD+ repletion.
- Pharmaceutical Sciences: NAD+ nasal spray is studied for coenzyme bioavailability optimization via intranasal delivery. Research examines spray formulation parameters (pH, tonicity, viscosity), NAD+ stability in aqueous nasal formulations, the effect of mucosal absorption enhancers, and comparative bioavailability against oral, sublingual, and intravenous NAD+ delivery routes.
- Gerontology: NAD+ spray is studied for non-invasive NAD+ repletion in aging intervention research. Research examines whether intranasal delivery can achieve therapeutically relevant NAD+ elevation in elderly subjects, restore age-related NAD+ decline, and produce measurable improvements in mitochondrial function, DNA repair capacity, and sirtuin-mediated longevity pathway activation.
Laboratory Preparation Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved and the solution appears clear, as shown in the vial image.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
