GLP-2 (TZ)
Dual GIP + GLP-1 Receptor Agonist
CAS: 2023788-19-2
Formula: C225H348N48O68
M.W.: 4813.5251 g/mol
Purity: 99%+ HPLC Verified
Ref No.:G2T-0005VI
Ref No.:G2T-0010VI
For Research Use Only (RUO)
Not for human or veterinary use.
GLP-2 (TZ)
Category
GLP / Metabolic Research
CAS Number
2023788-19-2
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in lyophilized powder form.
GLP-2 (TZ) is a dual-agonist peptide studied in laboratory research for its simultaneous activation of GIP and GLP-1 receptors. Research examines this “twincretin” mechanism’s metabolic- and glycemic-related signaling relative to GLP-1 single-agonists, providing a research tool for incretin biology in animal models. For laboratory research use only.
Description
GLP-2 (TZ) is a dual-agonist peptide studied in laboratory research for its simultaneous activation of GIP and GLP-1 receptors. Research examines this "twincretin" mechanism's metabolic- and glycemic-related signaling relative to GLP-1 single-agonists, providing a research tool for incretin biology in animal models. For laboratory research use only.Chemical Information
CAS Number
2023788-19-2
Purity
99%+ HPLC Verified
Molecular Formula
C225H348N48O68
Molar Mass
4813.5251 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Metabolic Research: GLP-2 (TZ) is investigated as a dual GIP/GLP-1 receptor agonist in experimental metabolic models. Research examines adipose-tissue responses, glycemic biomarkers, receptor trafficking, biased agonism, and tissue-specific signaling relative to single-receptor agonists.
- Endocrinology Research: GLP-2 (TZ) is studied for its influence on insulin sensitivity, pancreatic beta-cell activity, glucose-dependent insulin signaling, glucagon regulation, lipid metabolism, and adipose-tissue remodeling. Investigations also characterize concentration-response relationships and metabolic adaptation during extended observation periods.
- Hepatology Research: GLP-2 (TZ) is evaluated in experimental models of hepatic steatosis and metabolic liver dysfunction. Research endpoints include hepatic lipid accumulation, inflammatory signaling, insulin-pathway activity, and potential interactions between liver-specific responses and broader adipose-tissue changes.
- Cardiovascular Research: GLP-2 (TZ) is studied for its effects on cardiovascular and metabolic biomarkers. Investigated parameters include vascular function, lipid profiles, inflammatory mediators, atherosclerosis-associated signaling, and relationships between metabolic pathway modulation and cardiovascular tissue responses.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for GLP-2 (TZ) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
GLP-2 (TZ) is a dual-agonist peptide studied in laboratory research for its simultaneous activation of GIP and GLP-1 receptors. Research examines this "twincretin" mechanism's metabolic- and glycemic-related signaling relative to GLP-1 single-agonists, providing a research tool for incretin biology in animal models. For laboratory research use only.Chemical Information
CAS Number
2023788-19-2
Purity
99%+ HPLC Verified
Molecular Formula
C225H348N48O68
Molar Mass
4813.5251 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Metabolic Research: GLP-2 (TZ) is investigated as a dual GIP/GLP-1 receptor agonist in experimental metabolic models. Research examines adipose-tissue responses, glycemic biomarkers, receptor trafficking, biased agonism, and tissue-specific signaling relative to single-receptor agonists.
- Endocrinology Research: GLP-2 (TZ) is studied for its influence on insulin sensitivity, pancreatic beta-cell activity, glucose-dependent insulin signaling, glucagon regulation, lipid metabolism, and adipose-tissue remodeling. Investigations also characterize concentration-response relationships and metabolic adaptation during extended observation periods.
- Hepatology Research: GLP-2 (TZ) is evaluated in experimental models of hepatic steatosis and metabolic liver dysfunction. Research endpoints include hepatic lipid accumulation, inflammatory signaling, insulin-pathway activity, and potential interactions between liver-specific responses and broader adipose-tissue changes.
- Cardiovascular Research: GLP-2 (TZ) is studied for its effects on cardiovascular and metabolic biomarkers. Investigated parameters include vascular function, lipid profiles, inflammatory mediators, atherosclerosis-associated signaling, and relationships between metabolic pathway modulation and cardiovascular tissue responses.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for GLP-2 (TZ) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
