Semax (Spray)
ACTH Analog – Nootropic (Nasal)
CAS: 80714-61-0
Formula: C37H51N9O10S
M.W.: 813.9255 g/mol
Purity: 99%+ HPLC Verified
Ref No.: SEM-0050SP
For Research Use Only (RUO)
Not for human or veterinary use.
Semax (Spray)
Category
GH / Neuro / Misc
CAS Number
80714-61-0
Form Factor
Nasal Spray
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in freeze dried powder form.
Semax Nasal Spray delivers the nootropic peptide Semax via intranasal administration, providing enhanced CNS bioavailability by bypassing the blood-brain barrier through direct nasal-to-brain transport. It preserves all established neurotrophic properties — BDNF/NGF upregulation, neuroprotection, and cognitive enhancement.
Description
Semax Nasal Spray delivers the nootropic peptide Semax via intranasal administration, providing enhanced CNS bioavailability by bypassing the blood-brain barrier through direct nasal-to-brain transport. It preserves all established neurotrophic properties — BDNF/NGF upregulation, neuroprotection, and cognitive enhancement.Chemical Information
CAS Number
80714-61-0
Purity
99%+ HPLC Verified
Molecular Formula
C37H51N9O10S
Molar Mass
813.9255 g/mol
Form Factor
Nasal Spray
Synonyms
Research Applications
- Intranasal Neurology: Semax nasal spray is studied for nose-to-brain nootropic delivery that bypasses the blood-brain barrier. Research examines the distribution of nasally administered Semax in brain regions associated with memory and cognition, the bioavailability achieved compared to systemic injection, and the correlation between brain peptide levels and cognitive performance outcomes.
- Cognitive Enhancement: Nasal Semax is studied for rapid-onset neurotrophic factor modulation. Research examines whether intranasal delivery produces faster BDNF and NGF elevation in the CNS compared to other routes, and whether this translates to more immediate cognitive enhancement effects useful for acute cognitive demand situations in research settings.
- Pharmaceutical Sciences: Semax nasal spray formulation research focuses on optimizing nasal peptide bioavailability. Studies examine spray droplet characteristics, mucoadhesive formulation additives, preservative system compatibility, and long-term storage stability to develop nasal peptide delivery platforms applicable to Semax and other CNS-active peptides.
Reconstitution Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for Semax (Spray) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
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Research Database
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