GLP-1 (SG)
GLP-1 Receptor Agonist
CAS: 910463-68-2
Formula: C187H291N45O59
M.W.: 4113.5751 g/mol
Purity: 99%+ HPLC Verified
Ref No.:G1S-0005VI
Ref No.:G1S-0010VI
For Research Use Only (RUO)
Not for human or veterinary use.
GLP-1 (SG)
Category
GLP / Metabolic Research
CAS Number
910463-68-2
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in lyophilized powder form.
GLP-1 (SG) is a GLP-1 receptor agonist studied in laboratory research as a mimetic of the incretin hormone glucagon-like peptide-1. Research examines its interaction with glucose-dependent insulin-secretion pathways, glucagon-related signaling, gastric-emptying mechanisms, and central appetite-regulation-related signaling, including emerging neuroprotective and anti-inflammatory research areas, in animal models. For laboratory research use only.
Description
GLP-1 (SG) is a GLP-1 receptor agonist studied in laboratory research as a mimetic of the incretin hormone glucagon-like peptide-1. Research examines its interaction with glucose-dependent insulin-secretion pathways, glucagon-related signaling, gastric-emptying mechanisms, and central appetite-regulation-related signaling, including emerging neuroprotective and anti-inflammatory research areas, in animal models. For laboratory research use only.Chemical Information
CAS Number
910463-68-2
Purity
99%+ HPLC Verified
Molecular Formula
C187H291N45O59
Molar Mass
4113.5751 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Endocrinology: GLP-1 (SG) is a primary research compound in endocrinology for studying glucose-dependent insulin secretion and incretin biology. Research examines its effects on pancreatic beta-cell function, glucose transporter expression, and the mechanisms by which GLP-1 receptor activation improves glycemic control without the hypoglycemic risk associated with insulin secretagogues. Studies span from molecular receptor binding assays to whole-organism metabolic phenotyping.
- Metabolic Research: GLP-1 (SG) is extensively studied in preclinical models for its effects on appetite-regulating neurocircuitry, gastric emptying kinetics, and metabolic endpoints. Research examines GLP-1 receptor activation in hypothalamic and brainstem feeding centers, its influence on caloric intake behavior, and dose-dependent changes in adipose tissue markers in animal models. Studies focus on mechanism-of-action characterization rather than therapeutic outcomes.
- Cardiology: Emerging cardiovascular research positions GLP-1 (SG) as a cardiometabolic compound with direct cardioprotective effects beyond glycemic control. Studies investigate its impact on atherosclerosis progression, myocardial ischemia-reperfusion injury, blood pressure regulation, and inflammatory biomarkers associated with cardiovascular risk. Large outcomes trials have demonstrated significant reductions in major adverse cardiovascular events (MACE).
- Neuroscience: GLP-1 (SG) is increasingly studied in neuroscience for neuroprotective effects in Alzheimer's and Parkinson's disease models. GLP-1 receptors are expressed throughout the brain, and research demonstrates reduced neuroinflammation, enhanced synaptic plasticity, and protection against amyloid-beta toxicity. Preclinical models are being used to study cognitive outcomes in subjects with neurodegenerative conditions.
- Nephrology: GLP-1 (SG) is studied for renal protective effects in diabetic kidney disease models. Research demonstrates reduced albuminuria, attenuation of glomerular hyperfiltration, and decreased tubulointerstitial fibrosis. The mechanisms appear to involve both direct renal GLP-1 receptor activation and indirect benefits from improved glycemic and hemodynamic control.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for GLP-1 (SG) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
GLP-1 (SG) is a GLP-1 receptor agonist studied in laboratory research as a mimetic of the incretin hormone glucagon-like peptide-1. Research examines its interaction with glucose-dependent insulin-secretion pathways, glucagon-related signaling, gastric-emptying mechanisms, and central appetite-regulation-related signaling, including emerging neuroprotective and anti-inflammatory research areas, in animal models. For laboratory research use only.Chemical Information
CAS Number
910463-68-2
Purity
99%+ HPLC Verified
Molecular Formula
C187H291N45O59
Molar Mass
4113.5751 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Endocrinology: GLP-1 (SG) is a primary research compound in endocrinology for studying glucose-dependent insulin secretion and incretin biology. Research examines its effects on pancreatic beta-cell function, glucose transporter expression, and the mechanisms by which GLP-1 receptor activation improves glycemic control without the hypoglycemic risk associated with insulin secretagogues. Studies span from molecular receptor binding assays to whole-organism metabolic phenotyping.
- Metabolic Research: GLP-1 (SG) is extensively studied in preclinical models for its effects on appetite-regulating neurocircuitry, gastric emptying kinetics, and metabolic endpoints. Research examines GLP-1 receptor activation in hypothalamic and brainstem feeding centers, its influence on caloric intake behavior, and dose-dependent changes in adipose tissue markers in animal models. Studies focus on mechanism-of-action characterization rather than therapeutic outcomes.
- Cardiology: Emerging cardiovascular research positions GLP-1 (SG) as a cardiometabolic compound with direct cardioprotective effects beyond glycemic control. Studies investigate its impact on atherosclerosis progression, myocardial ischemia-reperfusion injury, blood pressure regulation, and inflammatory biomarkers associated with cardiovascular risk. Large outcomes trials have demonstrated significant reductions in major adverse cardiovascular events (MACE).
- Neuroscience: GLP-1 (SG) is increasingly studied in neuroscience for neuroprotective effects in Alzheimer's and Parkinson's disease models. GLP-1 receptors are expressed throughout the brain, and research demonstrates reduced neuroinflammation, enhanced synaptic plasticity, and protection against amyloid-beta toxicity. Preclinical models are being used to study cognitive outcomes in subjects with neurodegenerative conditions.
- Nephrology: GLP-1 (SG) is studied for renal protective effects in diabetic kidney disease models. Research demonstrates reduced albuminuria, attenuation of glomerular hyperfiltration, and decreased tubulointerstitial fibrosis. The mechanisms appear to involve both direct renal GLP-1 receptor activation and indirect benefits from improved glycemic and hemodynamic control.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for GLP-1 (SG) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
