GLP-1 (SG)

GLP-1 Receptor Agonist

CAS: 2023788-19-2

Formula: C₂₂₅H₃₄₈N₄₈O₆₈

M.W.: 4813.53 g/mol

Purity: 99%+ HPLC Verified

Ref No.:G1S-0005VI

For Research Use Only (RUO)

Not for human or veterinary use.

COA Included With Every Order

Third-Party Lab Tested

Cold-Chain Packaging Included

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99%+ HPLC Verified Purity

GLP-1 (SG)

Name: GLP-1 (SG)
SKU: glp-1-sg
Availability: InStock

Category

GLP / Metabolic

CAS Number

2023788-19-2

Form Factor

Lyophilized Powder

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GLP-1 (SG) is a GLP-1 receptor agonist that mimics the incretin hormone glucagon-like peptide-1. It stimulates glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and activates central appetite-regulation centers, with emerging research into neuroprotective and anti-inflammatory properties.

CAS Number

910463-68-2

Purity

99%+ HPLC Verified

Molecular Formula

C₁₈₇H₂₉₁N₄₅O₅₉

Molar Mass

4113.5751 g/mol

Form Factor

Lyophilized Powder

Synonyms

Semaglutide Wegovy® Rybelsus®

Endocrinology: GLP-1 (SG) is a primary research compound in endocrinology for studying glucose-dependent insulin secretion and incretin biology. Research examines its effects on pancreatic beta-cell function, glucose transporter expression, and the mechanisms by which GLP-1 receptor activation improves glycemic control without the hypoglycemic risk associated with insulin secretagogues. Studies span from molecular receptor binding assays to whole-organism metabolic phenotyping.
Obesity Research: GLP-1 (SG) is extensively studied for its appetite-regulating and weight management properties. Research demonstrates that GLP-1 receptor activation in hypothalamic appetite centers reduces caloric intake, slows gastric emptying, and promotes satiety signaling. Clinical-grade studies examine dose-dependent weight loss, visceral fat reduction, and the durability of metabolic improvements during and after treatment periods.
Cardiology: Emerging cardiovascular research positions GLP-1 (SG) as a cardiometabolic compound with direct cardioprotective effects beyond glycemic control. Studies investigate its impact on atherosclerosis progression, myocardial ischemia-reperfusion injury, blood pressure regulation, and inflammatory biomarkers associated with cardiovascular risk. Large outcomes trials have demonstrated significant reductions in major adverse cardiovascular events (MACE).
Neuroscience: GLP-1 (SG) is increasingly studied in neuroscience for neuroprotective effects in Alzheimer's and Parkinson's disease models. GLP-1 receptors are expressed throughout the brain, and research demonstrates reduced neuroinflammation, enhanced synaptic plasticity, and protection against amyloid-beta toxicity. Clinical trials are actively investigating cognitive outcomes in patients with neurodegenerative conditions.
Nephrology: GLP-1 (SG) is studied for renal protective effects in diabetic kidney disease models. Research demonstrates reduced albuminuria, attenuation of glomerular hyperfiltration, and decreased tubulointerstitial fibrosis. The mechanisms appear to involve both direct renal GLP-1 receptor activation and indirect benefits from improved glycemic and hemodynamic control.

Reconstitution Protocol

1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

Wear nitrile gloves and safety goggles when handling research compounds.
Work in a clean, controlled environment (laminar flow hood recommended).
Dispose of sharps and used materials in approved biohazard containers.
This product is for laboratory research use only (RUO) — not for human or veterinary use.

Quality Assurance Standards

Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.

Certificate of Analysis

Latest COA for GLP-1 (SG) — independently tested via HPLC and Mass Spectrometry.

COA-GLP1-09-2025

Testing Methodology

Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.

• HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
• Mass Spectrometry — Validates molecular identity and correct sequence.
• Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
• Sterility — Microbial contamination testing per USP standards.