TB-500 (Spray)
Thymosin Beta-4 (Nasal)
CAS: 77591-33-4
Formula: C212H350N56O78S
M.W.: 4963.4421 g/mol
Purity: 99%+ HPLC Verified
Ref No.: TB-0030SP
For Research Use Only (RUO)
Not for human or veterinary use.
TB-500 (Spray)
Category
Tissue Repair / Regenerative Research
CAS Number
77591-33-4
Form Factor
Nasal Spray
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in nasal spray form.
TB-500 Nasal Spray delivers Thymosin Beta-4 intranasally for systemic absorption. It preserves TB-500’s biological activities — actin upregulation, cell migration promotion, anti-inflammatory signaling, and wound healing support — while enabling research into nasal peptide delivery pharmacokinetics.
Description
TB-500 Nasal Spray delivers Thymosin Beta-4 intranasally for systemic absorption. It preserves TB-500's biological activities — actin upregulation, cell migration promotion, anti-inflammatory signaling, and wound healing support — while enabling research into nasal peptide delivery pharmacokinetics.Chemical Information
CAS Number
77591-33-4
Purity
99%+ HPLC Verified
Molecular Formula
C212H350N56O78S
Molar Mass
4963.4421 g/mol
Form Factor
Nasal Spray
Synonyms
Research Applications
- Intranasal Drug Delivery: TB-500 nasal spray is studied for its pharmacokinetic profile when delivered via the nasal mucosa. Research examines absorption kinetics, systemic peptide distribution, and bioavailability compared to subcutaneous injection. The nasal route offers a non-invasive alternative for chronic TB-500 administration protocols in tissue repair and regenerative medicine studies.
- Regenerative Medicine: Nasally administered TB-500 is investigated for its ability to produce systemic tissue repair effects through a non-invasive delivery route. Studies compare wound healing, cell migration promotion, and anti-inflammatory outcomes between nasal and injected TB-500, determining whether the convenience of nasal delivery can maintain therapeutic efficacy for extended research protocols.
- Pharmaceutical Sciences: TB-500 nasal spray formulations are studied for stability, optimal particle size, mucosal adhesion, and preservative compatibility. As a 43-amino-acid peptide, TB-500 presents unique formulation challenges that are relevant to broader nasal peptide delivery research and the development of non-injectable peptide therapeutics.
Reconstitution Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for TB-500 (Spray) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
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Research Database
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