NAD+ (buffered)
Nicotinamide Adenine Dinucleotide
CAS: 53-84-9
Formula: C21H28N7O14P2
M.W.: 664.4242 g/mol
Purity: 99%+ HPLC Verified
Ref No.:NAD-0500VI
For Research Use Only (RUO)
Not for human or veterinary use.
NAD+ (buffered)
Category
GH / Neuro / Misc Research
CAS Number
53-84-9
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in lyophilized powder form.
NAD+ (nicotinamide adenine dinucleotide) is an endogenous coenzyme involved in cellular redox reactions and serves as a substrate for sirtuins, PARPs, and CD38. Research examines age-associated changes in NAD+ availability and their relationships with mitochondrial bioenergetics, DNA-repair activity, cellular stress responses, and sirtuin-dependent signaling pathways. For laboratory research use only.
Description
NAD+ (nicotinamide adenine dinucleotide) is an endogenous coenzyme involved in cellular redox reactions and serves as a substrate for sirtuins, PARPs, and CD38. Research examines age-associated changes in NAD+ availability and their relationships with mitochondrial bioenergetics, DNA-repair activity, cellular stress responses, and sirtuin-dependent signaling pathways. For laboratory research use only.Chemical Information
CAS Number
53-84-9
Purity
99%+ HPLC Verified
Molecular Formula
C21H28N7O14P2
Molar Mass
664.4242 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Longevity Research: NAD+ is investigated as a substrate for sirtuin- and PARP-associated pathways in experimental aging models. Research examines age-related changes in NAD+ availability and their relationships with sirtuin activity, genome maintenance, cellular senescence, and metabolic regulation. Buffered formulations are evaluated for physicochemical stability, pH control, and tissue-response characteristics.
- Neuroscience Research: NAD+ is studied for its role in neuronal stress-response and survival pathways. Research examines SIRT1-associated signaling, PARP-1-dependent DNA repair, mitochondrial bioenergetics, oxidative-stress regulation, and age-related molecular changes in neural tissue.
- Mitochondrial-Biology Research: NAD+ is evaluated as a redox cofactor involved in cellular respiration and metabolic electron transfer. Investigations focus on NAD+/NADH ratios, respiratory-complex activity, oxidative phosphorylation, mitochondrial membrane potential, and bioenergetic responses in models of mitochondrial dysfunction.
- DNA-Repair Research: NAD+ is studied as a substrate for poly(ADP-ribose) polymerases. Research examines how changes in NAD+ availability influence PARP activity, DNA-damage responses, chromatin regulation, genomic stability, and cellular stress signaling.
- Metabolic Research: NAD+ is investigated for its central role in cellular energy metabolism. Research endpoints include glycolysis, the tricarboxylic-acid cycle, fatty-acid oxidation, insulin-signaling pathways, substrate utilization, and metabolic adaptation.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for NAD+ (buffered) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
NAD+ (nicotinamide adenine dinucleotide) is an endogenous coenzyme involved in cellular redox reactions and serves as a substrate for sirtuins, PARPs, and CD38. Research examines age-associated changes in NAD+ availability and their relationships with mitochondrial bioenergetics, DNA-repair activity, cellular stress responses, and sirtuin-dependent signaling pathways. For laboratory research use only.Chemical Information
CAS Number
53-84-9
Purity
99%+ HPLC Verified
Molecular Formula
C21H28N7O14P2
Molar Mass
664.4242 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Longevity Research: NAD+ is investigated as a substrate for sirtuin- and PARP-associated pathways in experimental aging models. Research examines age-related changes in NAD+ availability and their relationships with sirtuin activity, genome maintenance, cellular senescence, and metabolic regulation. Buffered formulations are evaluated for physicochemical stability, pH control, and tissue-response characteristics.
- Neuroscience Research: NAD+ is studied for its role in neuronal stress-response and survival pathways. Research examines SIRT1-associated signaling, PARP-1-dependent DNA repair, mitochondrial bioenergetics, oxidative-stress regulation, and age-related molecular changes in neural tissue.
- Mitochondrial-Biology Research: NAD+ is evaluated as a redox cofactor involved in cellular respiration and metabolic electron transfer. Investigations focus on NAD+/NADH ratios, respiratory-complex activity, oxidative phosphorylation, mitochondrial membrane potential, and bioenergetic responses in models of mitochondrial dysfunction.
- DNA-Repair Research: NAD+ is studied as a substrate for poly(ADP-ribose) polymerases. Research examines how changes in NAD+ availability influence PARP activity, DNA-damage responses, chromatin regulation, genomic stability, and cellular stress signaling.
- Metabolic Research: NAD+ is investigated for its central role in cellular energy metabolism. Research endpoints include glycolysis, the tricarboxylic-acid cycle, fatty-acid oxidation, insulin-signaling pathways, substrate utilization, and metabolic adaptation.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for NAD+ (buffered) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
