Semax
ACTH Analog – Nootropic
CAS: 80714-61-0
Formula: C37H51N9O10S
M.W.: 813.9255 g/mol
Purity: 99%+ HPLC Verified
Ref No.: SEM-0005VI
For Research Use Only (RUO)
Not for human or veterinary use.
Semax
Category
GH / Neuro / Misc Research
CAS Number
80714-61-0
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in lyophilized powder form.
Semax is a synthetic ACTH(4-10) analog developed for stroke and cognitive disorders. It upregulates BDNF and NGF, modulates serotonergic and dopaminergic neurotransmission, and has received regulatory approval in Russia for stroke treatment. Research shows improvements in memory, attention, and neuroprotection.
Description
Semax is a synthetic ACTH(4-10) analog developed for stroke and cognitive disorders. It upregulates BDNF and NGF, modulates serotonergic and dopaminergic neurotransmission, and has received regulatory approval in Russia for stroke treatment. Research shows improvements in memory, attention, and neuroprotection.Chemical Information
CAS Number
80714-61-0
Secondary CAS
183557-49-9
Purity
99%+ HPLC Verified
Molecular Formula
C37H51N9O10S
Molar Mass
813.9255 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Neurology: Semax is studied in stroke recovery and ischemic neuroprotection research, with regulatory approval in Russia for acute stroke treatment. Research examines its effects on infarct volume reduction, neurological deficit scores, and functional recovery following ischemic events. Studies investigate the mechanisms of neuroprotection, including BDNF/NGF upregulation, anti-apoptotic signaling, and cerebrovascular blood flow modulation.
- Cognitive Science: Semax is extensively studied for its nootropic effects on memory formation, attention, and executive function. Research demonstrates enhanced performance on spatial memory tasks, improved working memory capacity, and accelerated cognitive processing speed. Studies examine whether these effects are mediated through neurotrophic factor upregulation, cholinergic system modulation, or dopaminergic pathway enhancement.
- Neuropharmacology: Semax is a model compound for studying BDNF and NGF upregulation mechanisms. Research examines the time course of neurotrophic factor elevation, the receptor systems involved, and the downstream effects on synaptic plasticity, long-term potentiation, and dendritic morphology. These fundamental studies inform therapeutic development for neurodegenerative and cognitive disorders.
- Clinical Neuroscience: Semax serves as one of the few regulatory-approved nootropic peptides, providing validated clinical study models for cognitive enhancement research. Russian clinical data spanning decades provides a foundation for studying long-term nootropic efficacy, safety, and the translation of preclinical neurotrophic effects into measurable cognitive outcomes in human subjects.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
Semax is a synthetic ACTH(4-10) analog developed for stroke and cognitive disorders. It upregulates BDNF and NGF, modulates serotonergic and dopaminergic neurotransmission, and has received regulatory approval in Russia for stroke treatment. Research shows improvements in memory, attention, and neuroprotection.Chemical Information
CAS Number
80714-61-0
Secondary CAS
183557-49-9
Purity
99%+ HPLC Verified
Molecular Formula
C37H51N9O10S
Molar Mass
813.9255 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Neurology: Semax is studied in stroke recovery and ischemic neuroprotection research, with regulatory approval in Russia for acute stroke treatment. Research examines its effects on infarct volume reduction, neurological deficit scores, and functional recovery following ischemic events. Studies investigate the mechanisms of neuroprotection, including BDNF/NGF upregulation, anti-apoptotic signaling, and cerebrovascular blood flow modulation.
- Cognitive Science: Semax is extensively studied for its nootropic effects on memory formation, attention, and executive function. Research demonstrates enhanced performance on spatial memory tasks, improved working memory capacity, and accelerated cognitive processing speed. Studies examine whether these effects are mediated through neurotrophic factor upregulation, cholinergic system modulation, or dopaminergic pathway enhancement.
- Neuropharmacology: Semax is a model compound for studying BDNF and NGF upregulation mechanisms. Research examines the time course of neurotrophic factor elevation, the receptor systems involved, and the downstream effects on synaptic plasticity, long-term potentiation, and dendritic morphology. These fundamental studies inform therapeutic development for neurodegenerative and cognitive disorders.
- Clinical Neuroscience: Semax serves as one of the few regulatory-approved nootropic peptides, providing validated clinical study models for cognitive enhancement research. Russian clinical data spanning decades provides a foundation for studying long-term nootropic efficacy, safety, and the translation of preclinical neurotrophic effects into measurable cognitive outcomes in human subjects.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
