Selank
Tuftsin Analog – Anxiolytic
CAS: 129954-34-3
Formula: C33H57N11O9
M.W.: 751.8745 g/mol
Purity: 99%+ HPLC Verified
Ref No.: SEL-0005VI
For Research Use Only (RUO)
Not for human or veterinary use.
Selank
Category
GH / Neuro / Misc
CAS Number
129954-34-3
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in freeze dried powder form.
Selank is a synthetic heptapeptide analog of tuftsin that functions as an anxiolytic and nootropic through GABAergic modulation, enkephalin stabilization, and BDNF upregulation. Unlike benzodiazepines, it produces anti-anxiety effects without sedation, cognitive impairment, or dependence potential.
Description
Selank is a synthetic heptapeptide analog of tuftsin that functions as an anxiolytic and nootropic through GABAergic modulation, enkephalin stabilization, and BDNF upregulation. Unlike benzodiazepines, it produces anti-anxiety effects without sedation, cognitive impairment, or dependence potential.Chemical Information
CAS Number
129954-34-3
Secondary CAS
336181-69-8
Purity
99%+ HPLC Verified
Molecular Formula
C33H57N11O9
Molar Mass
751.8745 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Neuropharmacology: Selank is studied as a novel anxiolytic that produces anti-anxiety effects through GABAergic modulation and enkephalin stabilization without the sedation, cognitive impairment, tolerance, or dependence seen with benzodiazepines. Research examines its binding profile across GABA receptor subtypes, its effects on endogenous enkephalin degradation, and the neural circuitry mediating its anxiolytic actions in preclinical anxiety models.
- Immunology: Selank is unique among nootropic peptides for its dual anxiolytic-immunomodulatory profile. As a synthetic tuftsin analog, it modulates cytokine expression profiles, enhances natural killer cell activity, and influences T-cell differentiation. Research examines how this immunomodulatory activity interacts with its CNS effects and whether immune regulation contributes to its anxiolytic mechanisms.
- Neuroscience: Selank is studied for its enhancement of brain-derived neurotrophic factor (BDNF) expression, a key mediator of neuroplasticity, learning, and memory formation. Research examines the hippocampal and cortical BDNF changes following Selank administration, their correlation with behavioral outcomes in learning paradigms, and the long-term neuroplasticity effects of chronic Selank treatment protocols.
- Psychiatry: In psychiatric research models, Selank is studied for anxiety and stress-response regulation without the drawbacks of conventional anxiolytics. Studies examine its effects on generalized anxiety, social anxiety, and stress-induced behavioral changes using validated animal models. Research compares its efficacy and side effect profile against benzodiazepines, SSRIs, and other first-line anxiolytic medications.
Reconstitution Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for Selank — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Stacking Considerations
Selank is an anxiolytic neuropeptide studied for cognitive enhancement and immune modulation.
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