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CJC-1295 (no DAC)

Category

GH / Neuro / Misc

CAS Number

448906-42-1

Form Factor

Lyophilized Powder

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CJC-1295 without DAC (Modified GRF 1-29) is a synthetic GHRH analog with four amino acid substitutions for improved stability. Without the Drug Affinity Complex, it produces shorter, pulsatile GH bursts that closely mimic the body’s natural secretion patterns while preserving feedback mechanisms.

CJC-1295 without DAC (Modified GRF 1-29) is a synthetic GHRH analog with four amino acid substitutions for improved stability. Without the Drug Affinity Complex, it produces shorter, pulsatile GH bursts that closely mimic the body's natural secretion patterns while preserving feedback mechanisms.

CAS Number

863288-34-0

Secondary CAS

863288-19-1

Purity

99%+ HPLC Verified

Molecular Formula

C152H252N44O42

Molar Mass

3367.8956 g/mol

Form Factor

Lyophilized Powder

Synonyms

Modified GRF (1-29) Mod GRF 1-29
  • Endocrinology: CJC-1295 (no DAC) is studied for its ability to stimulate pulsatile growth hormone release that closely mimics natural physiological secretion patterns. Research examines the amplitude and frequency of GH pulses following administration, the impact on downstream IGF-1 levels, and how the peptide's pharmacokinetic profile preserves hypothalamic-pituitary feedback mechanisms that maintain hormonal homeostasis.
  • Gerontology: CJC-1295 (no DAC) is investigated in gerontological research for its potential to address age-related growth hormone decline (somatopause). Studies examine whether restoring youthful GH pulsatility can reverse age-associated changes in body composition, metabolic rate, bone mineral density, and immune function without the adverse effects associated with exogenous GH replacement.
  • Sports Science: In exercise and recovery research, CJC-1295 (no DAC) is studied for its effects on post-exercise recovery kinetics, lean body composition, and metabolic efficiency. Research examines whether enhanced GH pulsatility accelerates muscle protein synthesis, reduces exercise-induced inflammation, and improves substrate utilization during physical activity.
  • Sleep Medicine: CJC-1295 (no DAC) is studied in the context of sleep physiology because growth hormone secretion is closely linked to slow-wave sleep. Research examines whether GHRH analog administration enhances nocturnal GH pulse amplitude, improves sleep architecture, and increases the proportion of deep restorative sleep stages associated with tissue repair and cognitive consolidation.

Reconstitution Protocol

  1. 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
  2. 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
  3. 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall β€” do not spray directly onto the powder.
  4. 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
  5. 5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20Β°C to 4Β°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8Β°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25Β°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) β€” not for human or veterinary use.

Learn More About Peptides

Explore our research library covering purity, synthesis, storage, solubility, and more.

Peptide Information

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Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.

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Stacking Considerations

CJC-1295 (No DAC) / Mod GRF 1-29 is a GHRH analog that pairs naturally with GHRPs for pulsatile GH release.

    The classic GHRH + GHRP stack

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