CJC-1295 (no DAC)
Modified GRF (1-29) β GHRH Analog
CAS: 863288-34-0
Formula: C152H252N44O42
M.W.: 3367.8956 g/mol
Purity: 99%+ HPLC Verified
Ref No.: CJCN-0005VI
For Research Use Only (RUO)
Not for human or veterinary use.
CJC-1295 (no DAC)
Category
GH / Neuro / Misc
CAS Number
448906-42-1
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in freeze dried powder form.
CJC-1295 without DAC (Modified GRF 1-29) is a synthetic GHRH analog with four amino acid substitutions for improved stability. Without the Drug Affinity Complex, it produces shorter, pulsatile GH bursts that closely mimic the body’s natural secretion patterns while preserving feedback mechanisms.
Description
CJC-1295 without DAC (Modified GRF 1-29) is a synthetic GHRH analog with four amino acid substitutions for improved stability. Without the Drug Affinity Complex, it produces shorter, pulsatile GH bursts that closely mimic the body's natural secretion patterns while preserving feedback mechanisms.Chemical Information
CAS Number
863288-34-0
Secondary CAS
863288-19-1
Purity
99%+ HPLC Verified
Molecular Formula
C152H252N44O42
Molar Mass
3367.8956 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Endocrinology: CJC-1295 (no DAC) is studied for its ability to stimulate pulsatile growth hormone release that closely mimics natural physiological secretion patterns. Research examines the amplitude and frequency of GH pulses following administration, the impact on downstream IGF-1 levels, and how the peptide's pharmacokinetic profile preserves hypothalamic-pituitary feedback mechanisms that maintain hormonal homeostasis.
- Gerontology: CJC-1295 (no DAC) is investigated in gerontological research for its potential to address age-related growth hormone decline (somatopause). Studies examine whether restoring youthful GH pulsatility can reverse age-associated changes in body composition, metabolic rate, bone mineral density, and immune function without the adverse effects associated with exogenous GH replacement.
- Sports Science: In exercise and recovery research, CJC-1295 (no DAC) is studied for its effects on post-exercise recovery kinetics, lean body composition, and metabolic efficiency. Research examines whether enhanced GH pulsatility accelerates muscle protein synthesis, reduces exercise-induced inflammation, and improves substrate utilization during physical activity.
- Sleep Medicine: CJC-1295 (no DAC) is studied in the context of sleep physiology because growth hormone secretion is closely linked to slow-wave sleep. Research examines whether GHRH analog administration enhances nocturnal GH pulse amplitude, improves sleep architecture, and increases the proportion of deep restorative sleep stages associated with tissue repair and cognitive consolidation.
Reconstitution Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall β do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20Β°C to 4Β°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2β8Β°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25Β°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) β not for human or veterinary use.
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Stacking Considerations
CJC-1295 (No DAC) / Mod GRF 1-29 is a GHRH analog that pairs naturally with GHRPs for pulsatile GH release.
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