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99%+ HPLC Verified Purity

Sermorelin: High-Purity Research Peptide by Research Labs

Category

GH / Neuro / Misc Research

CAS Number

86168-78-7

Form Factor

Lyophilized Powder

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Sermorelin (GRF 1-29 NH2) is a synthetic analog of the first 29 amino acids of GHRH. It stimulates endogenous GH production while preserving natural feedback mechanisms and pulsatile secretion, providing a validated research compound for GHRH-axis biology with extensive prior clinical development data.

Sermorelin (GRF 1-29 NH2) is a synthetic analog of the first 29 amino acids of GHRH. It stimulates endogenous GH production while preserving natural feedback mechanisms and pulsatile secretion, providing a validated research compound for GHRH-axis biology with extensive prior clinical development data.

CAS Number

86168-78-7

Secondary CAS

114466-38-5

Purity

99%+ HPLC Verified

Molecular Formula

C149H246N44O42S

Molar Mass

3357.9319 g/mol

Form Factor

Lyophilized Powder

Synonyms

Sermorelin Acetate GRF (1-29) Geref®

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Safety & Compliance

  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) — not for human or veterinary use.

Quality Assurance Standards

Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.

Certificate of Analysis

Latest COA for Sermorelin — independently tested via HPLC and Mass Spectrometry.

Testing Methodology

Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.

  • • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
  • • Mass Spectrometry — Validates molecular identity and correct sequence.
  • • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
  • • Sterility — Microbial contamination testing per USP standards.

Learn More About Peptides

Explore our research library covering purity, synthesis, storage, solubility, and more.

Peptide Information

Research Database

Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.

View Research

Why Research Labs

  • Buy With Confidence

    COA links, HPLC data, and transparent pricing on every product page.

  • Fair Pricing, Higher Standards

    Transparent, competitive pricing without compromising the quality standards behind every batch.

  • Independently Tested

    Verified at 99%+ purity and sterility by third-party labs.

  • Shipped Same Day

    Order by 12 PM PT for guaranteed same-day shipping and tracking.

Complementary Research Peptides for GHRH Studies

Sermorelin (GRF 1-29 NH2) is a synthetic analog of the first 29 amino acids of GHRH. It stimulates endogenous GH production while preserving natural feedback mechanisms and pulsatile secretion, providing a validated research compound for GHRH-axis biology with extensive prior clinical development data.

CAS Number

86168-78-7

Secondary CAS

114466-38-5

Purity

99%+ HPLC Verified

Molecular Formula

C149H246N44O42S

Molar Mass

3357.9319 g/mol

Form Factor

Lyophilized Powder

Synonyms

Sermorelin Acetate GRF (1-29) Geref®

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Safety & Compliance

  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) — not for human or veterinary use.

Quality Assurance Standards

Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.

Certificate of Analysis

Latest COA for Sermorelin — independently tested via HPLC and Mass Spectrometry.

Testing Methodology

Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.

  • • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
  • • Mass Spectrometry — Validates molecular identity and correct sequence.
  • • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
  • • Sterility — Microbial contamination testing per USP standards.

Learn More About Peptides

Explore our research library covering purity, synthesis, storage, solubility, and more.

Peptide Information

Research Database

Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.

View Research

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Frequently Asked Questions (RUO Compliance)

1. What is the chemical composition of Sermorelin?

Sermorelin, also known as GRF (1-29), is a synthetic analog corresponding to the first 29 amino acids of growth hormone-releasing hormone (GHRH). Its molecular formula is C149H246N44O42S, with a molar mass of approximately 3357.93 g/mol (CAS 86168-78-7).

2. What research areas is Sermorelin studied in?

Preclinical and in vitro studies examine Sermorelin in relation to GHRH receptor signaling, pulsatile GH-related signaling and feedback regulation of the GH axis in experimental models.

3. How is the purity of each Sermorelin batch verified?

Each lot is analyzed by High-Performance Liquid Chromatography (HPLC) for chromatographic purity and by Mass Spectrometry (MS) to confirm molecular identity. Endotoxin (LAL) and sterility testing are also performed, and results are recorded on the batch Certificate of Analysis.

4. How should lyophilized Sermorelin be stored upon arrival?

Store unopened lyophilized vials at -20°C to 4°C in a dry, dark location. Under these conditions the powder remains stable for 24 months or longer.

5. What diluent is used to reconstitute Sermorelin for laboratory work?

Laboratories commonly reconstitute Sermorelin with sterile bacteriostatic water (0.9% benzyl alcohol) or sterile 0.9% sodium chloride, selected according to the assay protocol and how many times the vial will be sampled.

6. What is the proper technique for adding diluent to the Sermorelin vial?

Working under aseptic conditions, add the diluent slowly down the inside wall of the vial rather than directly onto the powder. Swirl gently until fully dissolved; do not shake or vortex.

7. How should reconstituted Sermorelin be stored?

Keep reconstituted solution refrigerated at 2–8°C and protected from light, and use it within 30 days. Avoid repeated freeze-thaw cycles, direct sunlight and temperatures above 25°C, which can degrade the peptide.

8. Where can researchers find the Certificate of Analysis for Sermorelin?

The current batch COA, including HPLC and mass spectrometry results, can be downloaded from the Lab Reports tab on this page and from the Research Labs Lab Reports library.

9. What sizes and synonyms apply to Sermorelin?

Sermorelin is supplied as 5 mg and 10 mg lyophilized vials (Ref. SER-0005VI and SER-0010VI). In the literature it may also appear as Sermorelin Acetate or GRF (1-29).

10. What is the regulatory status of Sermorelin sold by Research Labs?

This compound is supplied strictly for in vitro laboratory research by qualified personnel. It is not approved, intended or labeled for human, clinical, cosmetic or veterinary use.

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