Thymosin Alpha-1

Immunomodulatory Peptide

CAS: 62304-98-7

Formula: C₁₂₉H₂₁₅N₃₃O₅₅

M.W.: 3108.3081 g/mol

Purity: 99%+ HPLC Verified

Ref No.: THYA-0005VI

For Research Use Only (RUO)

Not for human or veterinary use.

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99%+ HPLC Verified Purity

Thymosin Alpha-1

Category

Healing / Growth / Cosmetic

CAS Number

62304-98-7

Form Factor

Lyophilized Powder

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5 mg

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Thymosin Alpha-1 is a naturally occurring 28-amino-acid peptide from thymic tissue that enhances T-cell maturation, activates dendritic cells, and stimulates toll-like receptor signaling. It has recei

CAS Number

62304-98-7

Purity

99%+ HPLC Verified

Molecular Formula

C₁₂₉H₂₁₅N₃₃O₅₅

Molar Mass

3108.3081 g/mol

Form Factor

Lyophilized Powder

Synonyms

Thymalfasin Tα1 Zadaxin®

Immunology: Thymosin Alpha-1 is studied for its comprehensive immunomodulatory effects including enhancement of T-cell maturation, activation of dendritic cells, stimulation of toll-like receptor signaling, and augmentation of natural killer cell cytotoxicity. Research examines the molecular mechanisms of immune reconstitution, the optimal dosing for different immunodeficiency states, and the duration of immunological enhancement following treatment courses.
Oncology: Thymosin Alpha-1 is studied as an immune surveillance enhancer and adjuvant in cancer immunotherapy research. Studies examine its ability to augment tumor-specific T-cell responses, enhance the efficacy of checkpoint inhibitors and cancer vaccines, and improve immune function in patients with chemotherapy-induced immunosuppression. Research investigates its role in the tumor microenvironment and its effects on immunosuppressive regulatory T-cell populations.
Hepatology: Thymosin Alpha-1 has received regulatory approval in over 35 countries for hepatitis B and C treatment, providing extensive clinical data for hepatology research. Studies examine the mechanisms of enhanced viral clearance, the relationship between T-cell reconstitution and viral response, and the combination strategies with direct-acting antivirals that optimize sustained virological response rates.
Vaccine Science: Thymosin Alpha-1 is studied as an immune adjuvant to amplify vaccine responses in immunocompromised populations. Research examines its ability to enhance antibody titers, T-cell memory formation, and vaccine efficacy in elderly subjects, HIV-infected individuals, and transplant recipients on immunosuppressive therapy. Studies investigate optimal timing and dosing for maximum adjuvant effect.

Reconstitution Protocol

1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

Wear nitrile gloves and safety goggles when handling research compounds.
Work in a clean, controlled environment (laminar flow hood recommended).
Dispose of sharps and used materials in approved biohazard containers.
This product is for laboratory research use only (RUO) — not for human or veterinary use.