SS-31
Mitochondria-Targeted Tetrapeptide (Elamipretide)
CAS: 736992-21-5
Formula: C32H49N9O5
M.W.: 611.78 g/mol
Purity: 99%+ HPLC Verified
Ref No.: SS-0010VI
Ref No.: SS-0050VI
For Research Use Only (RUO)
Not for human or veterinary use.
SS-31
Category
GH / Neuro / Misc Research
CAS Number
736992-21-5
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in lyophilized powder form.
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH₂. Experimental research examines its association with the inner mitochondrial membrane, interactions with cardiolipin, electron-transport-chain activity, oxidative-stress signaling, cellular bioenergetics, and age-associated mitochondrial changes. For laboratory research use only.
Description
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH₂. Experimental research examines its association with the inner mitochondrial membrane, interactions with cardiolipin, electron-transport-chain activity, oxidative-stress signaling, cellular bioenergetics, and age-associated mitochondrial changes. For laboratory research use only.Chemical Information
CAS Number
736992-21-5
Purity
99%+ HPLC Verified
Molecular Formula
C32H49N9O5
Molar Mass
611.78 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Mitochondrial-Biology Research: SS-31 is investigated as a cell-permeable peptide with affinity for the inner mitochondrial membrane. Research examines cardiolipin interactions, electron-transport-chain organization, membrane potential, oxidative phosphorylation, and mitochondrial responses under conditions of cellular dysfunction.
- Cardiovascular Research: SS-31 is studied in experimental models of cardiac dysfunction, ischemia–reperfusion injury, and cardiomyopathy. Research endpoints include mitochondrial respiration, cardiomyocyte viability, contractile-function measures, oxidative-stress signaling, and injury-associated tissue changes.
- Nephrology Research: SS-31 is evaluated in models of acute and chronic renal injury. Investigations assess tubular-cell mitochondrial structure, renal bioenergetics, oxidative damage, inflammatory signaling, and filtration-associated biomarkers.
- Gerontology Research: SS-31 is studied for its influence on age-associated mitochondrial changes. Research focuses on energy production, mitochondrial dynamics, cardiolipin integrity, reactive-oxygen-species signaling, and cellular-function markers in aged tissue models.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for SS-31 — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH₂. Experimental research examines its association with the inner mitochondrial membrane, interactions with cardiolipin, electron-transport-chain activity, oxidative-stress signaling, cellular bioenergetics, and age-associated mitochondrial changes. For laboratory research use only.Chemical Information
CAS Number
736992-21-5
Purity
99%+ HPLC Verified
Molecular Formula
C32H49N9O5
Molar Mass
611.78 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Mitochondrial-Biology Research: SS-31 is investigated as a cell-permeable peptide with affinity for the inner mitochondrial membrane. Research examines cardiolipin interactions, electron-transport-chain organization, membrane potential, oxidative phosphorylation, and mitochondrial responses under conditions of cellular dysfunction.
- Cardiovascular Research: SS-31 is studied in experimental models of cardiac dysfunction, ischemia–reperfusion injury, and cardiomyopathy. Research endpoints include mitochondrial respiration, cardiomyocyte viability, contractile-function measures, oxidative-stress signaling, and injury-associated tissue changes.
- Nephrology Research: SS-31 is evaluated in models of acute and chronic renal injury. Investigations assess tubular-cell mitochondrial structure, renal bioenergetics, oxidative damage, inflammatory signaling, and filtration-associated biomarkers.
- Gerontology Research: SS-31 is studied for its influence on age-associated mitochondrial changes. Research focuses on energy production, mitochondrial dynamics, cardiolipin integrity, reactive-oxygen-species signaling, and cellular-function markers in aged tissue models.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for SS-31 — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
