Melanotan-2
Melanocortin Receptor Agonist (MT-II)
CAS: 121062-08-6
Formula: C50H69N15O9
M.W.: 1024.1785 g/mol
Purity: 99%+ HPLC Verified
Ref No.: ML2-0010VI
For Research Use Only (RUO)
Not for human or veterinary use.
Melanotan-2
Category
GH / Neuro / Misc Research
CAS Number
121062-08-6
Form Factor
Lyophilized Powder
In stock, ready to ship
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Products are shipped in lyophilized powder form.
Melanotan II is a cyclic heptapeptide analogue of α-melanocyte-stimulating hormone studied for its interaction with melanocortin receptor subtypes MC1R–MC5R. Laboratory research examines its role in melanogenic signaling, energy-intake-regulation pathways, and receptor-specific signaling, and its MC4R activity is used in comparative research alongside related melanocortin analogues. For laboratory research use only.
Description
Melanotan II is a cyclic heptapeptide analogue of α-melanocyte-stimulating hormone studied for its interaction with melanocortin receptor subtypes MC1R–MC5R. Laboratory research examines its role in melanogenic signaling, energy-intake-regulation pathways, and receptor-specific signaling, and its MC4R activity is used in comparative research alongside related melanocortin analogues. For laboratory research use only.Chemical Information
CAS Number
121062-08-6
Secondary CAS
192568-05-7
Purity
99%+ HPLC Verified
Molecular Formula
C50H69N15O9
Molar Mass
1024.1785 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Dermatological Research: Melanotan II is investigated for melanocortin-mediated pigmentation through interactions with MC1R–MC5R. Research endpoints include melanogenesis kinetics, melanin synthesis, pigment distribution, melanocyte activity, and receptor-specific signaling. Neurobehavioral Research: Melanotan II is studied for MC4R-associated effects on central arousal and related neurobehavioral pathways. Comparative research examines melanocortin-receptor signaling involving Melanotan II, PT-141 (bremelanotide), and other α-MSH analogues. Metabolic Research: Melanotan II is evaluated for its influence on central energy-intake regulation and adipose-tissue metabolism. Investigations focus on MC4R-dependent hypothalamic signaling, feeding-behavior parameters, lipid mobilization, and lipolysis-associated pathways. Photobiology Research: Melanotan II is studied for its effects on melanogenesis independent of ultraviolet stimulation. Research examines melanin production, pigment persistence, ultraviolet-response biomarkers, and the relationship between induced pigmentation and cellular photoprotection.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for Melanotan-2 — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
Melanotan II is a cyclic heptapeptide analogue of α-melanocyte-stimulating hormone studied for its interaction with melanocortin receptor subtypes MC1R–MC5R. Laboratory research examines its role in melanogenic signaling, energy-intake-regulation pathways, and receptor-specific signaling, and its MC4R activity is used in comparative research alongside related melanocortin analogues. For laboratory research use only.Chemical Information
CAS Number
121062-08-6
Secondary CAS
192568-05-7
Purity
99%+ HPLC Verified
Molecular Formula
C50H69N15O9
Molar Mass
1024.1785 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Dermatological Research: Melanotan II is investigated for melanocortin-mediated pigmentation through interactions with MC1R–MC5R. Research endpoints include melanogenesis kinetics, melanin synthesis, pigment distribution, melanocyte activity, and receptor-specific signaling. Neurobehavioral Research: Melanotan II is studied for MC4R-associated effects on central arousal and related neurobehavioral pathways. Comparative research examines melanocortin-receptor signaling involving Melanotan II, PT-141 (bremelanotide), and other α-MSH analogues. Metabolic Research: Melanotan II is evaluated for its influence on central energy-intake regulation and adipose-tissue metabolism. Investigations focus on MC4R-dependent hypothalamic signaling, feeding-behavior parameters, lipid mobilization, and lipolysis-associated pathways. Photobiology Research: Melanotan II is studied for its effects on melanogenesis independent of ultraviolet stimulation. Research examines melanin production, pigment persistence, ultraviolet-response biomarkers, and the relationship between induced pigmentation and cellular photoprotection.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for Melanotan-2 — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
