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Snap-8

Category

Tissue Repair / Regenerative Research

CAS Number

868844-74-0

Form Factor

Lyophilized Powder

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SNAP-8 (Acetyl Octapeptide-3) mimics SNAP-25 to reduce neuromuscular signal transmission efficiency, decreasing muscle contraction in a mechanism analogous to — but far milder than — botulinum toxin.

SNAP-8 (Acetyl Octapeptide-3) mimics SNAP-25 to reduce neuromuscular signal transmission efficiency, decreasing muscle contraction in a mechanism analogous to — but far milder than — botulinum toxin.

CAS Number

868844-74-0

Purity

99%+ HPLC Verified

Molecular Formula

C41H70N16O16S

Molar Mass

1075.1523 g/mol

Form Factor

Lyophilized Powder

Synonyms

Acetyl Octapeptide-3 SNAP-8
  • Cosmetic Science: SNAP-8 (Acetyl Octapeptide-3) is studied for non-invasive wrinkle reduction through modulation of the SNARE complex assembly required for neuromuscular signal transmission. Research examines its ability to reduce muscle contraction intensity in facial expression muscles, the resulting decrease in dynamic wrinkle depth, and its comparative efficacy against other cosmetic peptides and non-peptide anti-aging actives.
  • Neuromuscular Pharmacology: SNAP-8 is studied for its mechanism of SNAP-25 modulation, mimicking a milder version of botulinum toxin's mechanism without the risk of complete muscle paralysis. Research examines the degree of neuromuscular junction efficiency reduction, the reversibility of effects, and the concentration-response relationship in isolated muscle preparations and in vivo dermal application models.
  • Dermatology: SNAP-8 is studied for expression line prevention and treatment in skin aging research. Clinical studies measure wrinkle depth reduction using profilometry, surface roughness analysis, and standardized photography. Research examines the timeline of clinical improvement, the durability of effects with continued application, and the synergistic potential with moisturizing and collagen-stimulating formulation ingredients.
  • Peptide Cosmeceuticals: SNAP-8 is a key compound in the development of peptide-based cosmeceutical products. Research examines topical formulation optimization including peptide stability in emulsions, skin penetration enhancement strategies, and the development of delivery systems that maximize dermal bioavailability. Studies compare different vehicle systems for optimal peptide activity retention and clinical efficacy.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Safety & Compliance

  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) — not for human or veterinary use.

Learn More About Peptides

Explore our research library covering purity, synthesis, storage, solubility, and more.

Peptide Information

Research Database

Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.

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COA Included With Every Order
Third-Party Lab Tested
Quality Guaranteed
Free Shipping on Orders $150+

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Stacking Considerations

Snap-8 is an anti-wrinkle octapeptide that modulates SNARE complex formation, often paired with skin-targeting peptides.

SNAP-8 (Acetyl Octapeptide-3) mimics SNAP-25 to reduce neuromuscular signal transmission efficiency, decreasing muscle contraction in a mechanism analogous to — but far milder than — botulinum toxin.

CAS Number

868844-74-0

Purity

99%+ HPLC Verified

Molecular Formula

C41H70N16O16S

Molar Mass

1075.1523 g/mol

Form Factor

Lyophilized Powder

Synonyms

Acetyl Octapeptide-3 SNAP-8
  • Cosmetic Science: SNAP-8 (Acetyl Octapeptide-3) is studied for non-invasive wrinkle reduction through modulation of the SNARE complex assembly required for neuromuscular signal transmission. Research examines its ability to reduce muscle contraction intensity in facial expression muscles, the resulting decrease in dynamic wrinkle depth, and its comparative efficacy against other cosmetic peptides and non-peptide anti-aging actives.
  • Neuromuscular Pharmacology: SNAP-8 is studied for its mechanism of SNAP-25 modulation, mimicking a milder version of botulinum toxin's mechanism without the risk of complete muscle paralysis. Research examines the degree of neuromuscular junction efficiency reduction, the reversibility of effects, and the concentration-response relationship in isolated muscle preparations and in vivo dermal application models.
  • Dermatology: SNAP-8 is studied for expression line prevention and treatment in skin aging research. Clinical studies measure wrinkle depth reduction using profilometry, surface roughness analysis, and standardized photography. Research examines the timeline of clinical improvement, the durability of effects with continued application, and the synergistic potential with moisturizing and collagen-stimulating formulation ingredients.
  • Peptide Cosmeceuticals: SNAP-8 is a key compound in the development of peptide-based cosmeceutical products. Research examines topical formulation optimization including peptide stability in emulsions, skin penetration enhancement strategies, and the development of delivery systems that maximize dermal bioavailability. Studies compare different vehicle systems for optimal peptide activity retention and clinical efficacy.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Safety & Compliance

  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) — not for human or veterinary use.

Learn More About Peptides

Explore our research library covering purity, synthesis, storage, solubility, and more.

Peptide Information

Research Database

Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.

View Research

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