CJC-1295 DAC
Long-Acting GHRH Analog (Drug Affinity Complex)
CAS: 446262-90-4
Formula: C165H269N47O46
M.W.: 3647.2766 g/mol
Purity: 99%+ HPLC Verified
Ref No.: CJCD-0005VI
For Research Use Only (RUO)
Not for human or veterinary use.
CJC-1295 DAC
Category
GH / Neuro / Misc
CAS Number
446262-90-4
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in freeze dried powder form.
CJC-1295 DAC is a long-acting GHRH analog featuring a Drug Affinity Complex that bonds with serum albumin, extending its half-life from ~30 minutes to 6-8 days. A single dose can elevate mean GH levels 2-10 fold and IGF-1 levels 1.5-3 fold for up to 6 days.
Description
CJC-1295 DAC is a long-acting GHRH analog featuring a Drug Affinity Complex that bonds with serum albumin, extending its half-life from ~30 minutes to 6-8 days. A single dose can elevate mean GH levels 2-10 fold and IGF-1 levels 1.5-3 fold for up to 6 days.Chemical Information
CAS Number
446262-90-4
Secondary CAS
863288-19-1
Purity
99%+ HPLC Verified
Molecular Formula
C165H269N47O46
Molar Mass
3647.2766 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Pharmacokinetics: CJC-1295 DAC is a key research compound for studying long-acting peptide delivery via albumin binding mechanisms. The Drug Affinity Complex extends the peptide's half-life from approximately 30 minutes to 6-8 days by enabling reversible binding to circulating serum albumin. Research examines the kinetics of albumin association/dissociation, sustained GH elevation profiles, and the implications for peptide drug design.
- Endocrinology: CJC-1295 DAC is studied for its unique ability to provide sustained growth hormone axis stimulation over extended periods. A single administration can elevate mean GH levels 2-10 fold and IGF-1 levels 1.5-3 fold for up to 6 days. Research examines the metabolic consequences of this sustained elevation versus the pulsatile patterns produced by shorter-acting GHRH analogs.
- Gerontology: In aging research, CJC-1295 DAC is studied for prolonged IGF-1 elevation in models of age-related decline. The extended half-life enables convenient dosing protocols for chronic studies examining the reversal of sarcopenia, osteopenia, and metabolic dysfunction associated with somatopause. Research compares long-term outcomes between sustained and pulsatile GH elevation strategies.
Reconstitution Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for CJC-1295 DAC — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Stacking Considerations
CJC-1295 with DAC provides sustained GH elevation and pairs with GHRPs and metabolic peptides.
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