Glutathione

Tripeptide Antioxidant

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

M.W.: 307.3235 g/mol

Purity: 99%+ HPLC Verified

Ref No.: GLU-1500VI

For Research Use Only (RUO)

Not for human or veterinary use.

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99%+ HPLC Verified Purity

Glutathione

Name: Glutathione
SKU: glutathione
Availability: InStock

Category

GH / Neuro / Misc

CAS Number

70-18-8

Form Factor

Lyophilized Powder

Select mg:

1500 mg

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Glutathione is the body’s primary intracellular antioxidant and detoxification molecule, present in virtually every cell. It neutralizes reactive oxygen species, supports xenobiotic metabolism, and pl

Glutathione is the body's primary intracellular antioxidant and detoxification molecule, present in virtually every cell. It neutralizes reactive oxygen species, supports xenobiotic metabolism, and pl

CAS Number

70-18-8

Purity

99%+ HPLC Verified

Molecular Formula

C₁₀H₁₇N₃O₆S

Molar Mass

307.3235 g/mol

Form Factor

Lyophilized Powder

Synonyms

L-Glutathione GSH γ-L-Glutamyl-L-cysteinyl-glycine

Toxicology: Glutathione is studied as the body's primary hepatoprotective and detoxification molecule. Research examines its role in Phase II conjugation reactions, xenobiotic metabolism, and protection against drug-induced liver injury. Studies investigate glutathione depletion-repletion dynamics, the threshold levels required for adequate hepatoprotection, and strategies for maintaining glutathione reserves during toxic exposures.
Immunology: Glutathione is studied for its critical role in lymphocyte function and oxidative stress defense within the immune system. Research demonstrates that T-cell activation, proliferation, and cytokine production are glutathione-dependent processes. Studies examine the relationship between intracellular glutathione levels and immune competence, particularly in immunocompromised states and chronic infections.
Dermatology: Glutathione is studied for melanogenesis modulation and skin brightening effects in dermatological research. Studies demonstrate inhibition of tyrosinase enzyme activity and switching of melanin synthesis from eumelanin (dark) to pheomelanin (light). Research examines the dose-response relationship for skin lightening, the reversibility of effects, and the formulation strategies for optimizing dermatological glutathione delivery.
Neuroscience: Glutathione is studied for oxidative stress protection in neurodegeneration research. Brain glutathione depletion correlates with Parkinson's disease progression, and research examines whether glutathione supplementation can slow neuronal loss, reduce oxidative damage markers, and preserve dopaminergic function. Studies investigate blood-brain barrier glutathione transport and CNS bioavailability optimization.

Reconstitution Protocol

1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

Wear nitrile gloves and safety goggles when handling research compounds.
Work in a clean, controlled environment (laminar flow hood recommended).
Dispose of sharps and used materials in approved biohazard containers.
This product is for laboratory research use only (RUO) — not for human or veterinary use.