Tesofensine (Capsules)

Triple Monoamine Reuptake Inhibitor

CAS: 402856-42-2

Formula: C₁₇H₂₃Cl₂NO

M.W.: 328.2772 g/mol

Purity: 99%+ HPLC Verified

Ref No.: TSF-0500TA

For Research Use Only (RUO)

Not for human or veterinary use.

COA Included With Every Order

Third-Party Lab Tested

Quality Guaranteed

Free Shipping on Orders $150+

99%+ HPLC Verified Purity

Tesofensine (Capsules)

Category

GLP / Metabolic Research

CAS Number

195875-84-4

Form Factor

Capsules

Select mg:

500 mcg (60 ct)

Clear

BUNDLE & SAVE

Quantity:

FREE Shipping on orders $150+ (after any discounts)

In stock, ready to ship

Ships same day before 12pm PST

Products are shipped in capsule form.

Tesofensine is a triple monoamine reuptake inhibitor blocking serotonin, norepinephrine, and dopamine reuptake. Phase II trials demonstrated 10-13% weight loss over 24 weeks, exceeding existing anti-obesity medications. The triple mechanism provides appetite suppression, enhanced thermogenesis, and mood-elevating effects.

CAS Number

402856-42-2

Purity

99%+ HPLC Verified

Molecular Formula

C₁₇H₂₃Cl₂NO

Molar Mass

328.2772 g/mol

Form Factor

Capsules

Synonyms

NS2330 Triple Reuptake Inhibitor

Obesity Research: Tesofensine capsules are studied for weight management through simultaneous inhibition of serotonin, norepinephrine, and dopamine reuptake. Phase II clinical trials demonstrated 10-13% body weight loss over 24 weeks — exceeding existing anti-obesity medications. Research examines the relative contribution of each monoamine pathway to the weight loss effect and the durability of response during extended treatment periods.
Neuropharmacology: Tesofensine is studied for its unique triple monoamine reuptake inhibition mechanism, combining the appetite-suppressing effects of serotonin reuptake inhibition with the thermogenic effects of norepinephrine reuptake inhibition and the mood and reward pathway effects of dopamine reuptake inhibition. Research examines the pharmacodynamic interactions between these three neurotransmitter systems and their combined effects on eating behavior.
Appetite Science: Tesofensine is studied for central appetite suppression mechanisms. Research examines its effects on hypothalamic appetite regulatory circuits, meal size and frequency, food preference (particularly for high-fat and high-sugar options), and the subjective experience of hunger and satiety. Studies investigate the neural basis of appetite reduction using neuroimaging and behavioral feeding paradigms.
Thermogenesis: Tesofensine is studied for metabolic rate enhancement through noradrenergic stimulation. Research examines changes in resting energy expenditure, thermic effect of food, and physical activity-related energy expenditure during treatment. Studies quantify the relative contributions of reduced caloric intake versus increased energy expenditure to the total weight loss achieved.

Reconstitution Protocol

1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall — do not spray directly onto the powder.
4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
5 Label the vial with the reconstitution date and concentration.

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Always note the reconstitution date on the vial label to track shelf life accurately.

Safety & Compliance

Wear nitrile gloves and safety goggles when handling research compounds.
Work in a clean, controlled environment (laminar flow hood recommended).
Dispose of sharps and used materials in approved biohazard containers.
This product is for laboratory research use only (RUO) — not for human or veterinary use.