Cagrilintide | GLP-1 (SG)
Amylin Analog + GLP-1 Receptor Agonist Blend
Blend Components:
Cagrilintide
CAS: 1415456-99-3
Formula: C194H312N54O59S2
M.W.: 4425.1146 g/mol
GLP-1 (SG)
CAS: 910463-68-2
Formula: C187H291N45O59
M.W.: 4113.5751 g/mol
Purity: 99%+ HPLC Verified
Ref No.:CGL-0002VI
Ref No.:CGL-0005VI
For Research Use Only (RUO)
Not for human or veterinary use.
Cagrilintide | GLP-1 (SG) (Blend)
Category
GLP / Metabolic
Form Factor
Lyophilized Powder
Blend Components
Cagrilintide
2.5 mg
5 mg
CAS: 1415456-99-3
GLP-1 (SG)
2.5 mg
5 mg
CAS: 910463-68-2
Cagrilintide
CAS
1415456-99-3
Formula
C194H312N54O59S2
Molar Mass
4425.1146 g/mol
GLP-1 (SG)
CAS
910463-68-2
Formula
C187H291N45O59
Molar Mass
4113.5751 g/mol
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in freeze dried powder form.
This dual-agonist blend combines Cagrilintide (long-acting amylin analog) with GLP-1 (SG) (GLP-1 receptor agonist) for synergistic metabolic research. Clinical data from the CagriSema program demonstrates unprecedented weight reduction exceeding 25% when both pathways are activated simultaneously, surpassing either agent alone.
Description
This dual-agonist blend combines Cagrilintide (long-acting amylin analog) with GLP-1 (SG) (GLP-1 receptor agonist) for synergistic metabolic research. Clinical data from the CagriSema program demonstrates unprecedented weight reduction exceeding 25% when both pathways are activated simultaneously, surpassing either agent alone.Chemical Information
Purity
99%+ HPLC Verified
Form Factor
Lyophilized Powder
Synonyms
Blend Components
Cagrilintide
2.5 mg
5 mg
CAS: 1415456-99-3
GLP-1 (SG)
2.5 mg
5 mg
CAS: 910463-68-2
Cagrilintide
CAS
1415456-99-3
Formula
C194H312N54O59S2
Molar Mass
4425.1146 g/mol
GLP-1 (SG)
CAS
910463-68-2
Formula
C187H291N45O59
Molar Mass
4113.5751 g/mol
Research Applications
- Obesity & Metabolic Research: The Cagrilintide | GLP-1 (SG) blend represents a dual-agonist approach combining amylin and GLP-1 receptor activation for synergistic weight management research. Clinical data from the CagriSema program demonstrates unprecedented weight reduction exceeding 25% when both pathways are activated simultaneously. Research examines the complementary mechanisms of amylin-mediated satiety signaling and GLP-1-driven insulin sensitization, appetite suppression, and delayed gastric emptying.
- Endocrinology: This combination is studied for its effects on the incretin-amylin hormonal axis and pancreatic beta-cell function. Research investigates how simultaneous amylin analog and GLP-1 receptor agonist administration modulates postprandial glucose excursions, insulin secretion dynamics, and glucagon suppression. Studies examine the potential for improved glycemic control beyond what either agent achieves independently, with implications for type 2 diabetes therapeutic development.
- Pharmaceutical Sciences: The Cagrilintide | GLP-1 (SG) combination is studied as a model for multi-target peptide therapeutics. Research focuses on the pharmacokinetic interactions between the two peptides, optimal dosing ratios, reconstitution stability, and the formulation science of co-lyophilized peptide blends. Studies also examine the long-acting acylation technology that extends cagrilintide's half-life for weekly dosing compatibility with GLP-1 (SG).
- Neuroscience of Appetite: This dual-agonist blend is investigated for its effects on central appetite regulation circuits. Research examines how combined amylin and GLP-1 receptor activation in the area postrema, nucleus tractus solitarius, and hypothalamic feeding centers produces enhanced satiety signaling compared to single-agent approaches. Studies map the neural pathways responsible for the synergistic reduction in food intake observed in preclinical and clinical models.
Reconstitution Protocol
- 1 Remove the flip-off cap and wipe the rubber stopper with an alcohol swab.
- 2 Using a sterile syringe, draw the desired volume of bacteriostatic water (BAC water).
- 3 Insert the needle into the vial at an angle and slowly dispense the water down the inside wall β do not spray directly onto the powder.
- 4 Gently swirl (do not shake) the vial until the powder is fully dissolved.
- 5 Label the vial with the reconstitution date and concentration.
Storage Conditions
Unreconstituted
Store at -20Β°C to 4Β°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2β8Β°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25Β°C.
Always note the reconstitution date on the vial label to track shelf life accurately.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) β not for human or veterinary use.
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