GLP-3 (RT)
Triple Agonist
CAS: 2381089-83-2
Formula: C221H342N46O68
M.W.: 4731.3263 g/mol
Purity: 99%+ HPLC Verified
Ref No.:RET-0005VI
Ref No.:RET-0010VI
Ref No.:RET-0015VI
For Research Use Only (RUO)
Not for human or veterinary use.
GLP-3 (RT)
Category
GLP / Metabolic Research
CAS Number
2381089-83-2
Form Factor
Lyophilized Powder
In stock, ready to ship
Ships same day before 12pm PST
Products are shipped in lyophilized powder form.
GLP-3 (RT) is a triple-agonist peptide simultaneously activating GLP-1, GIP, and glucagon receptors. Early preclinical data show pronounced metabolic endpoint changes at higher doses. The glucagon component adds thermogenic signaling and hepatic lipid oxidation absent from dual-agonists.
Description
GLP-3 (RT) is a triple-agonist peptide simultaneously activating GLP-1, GIP, and glucagon receptors. Early preclinical data show pronounced metabolic endpoint changes at higher doses. The glucagon component adds thermogenic signaling and hepatic lipid oxidation absent from dual-agonists.Chemical Information
CAS Number
2381089-83-2
Purity
99%+ HPLC Verified
Molecular Formula
C221H342N46O68
Molar Mass
4731.3263 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Metabolic Research: GLP-3 (RT) is investigated as a triple GLP-1, GIP, and glucagon receptor agonist in experimental metabolic models. Research focuses on adipose-tissue responses, multi-receptor signaling interactions, energy-balance regulation, and concentration-response relationships relative to single- and dual-receptor agonists.
- Hepatology Research: The glucagon-receptor activity of GLP-3 (RT) is studied for its influence on hepatic lipid oxidation and liver-fat metabolism. Experimental endpoints include hepatic lipid accumulation, fibrosis-associated markers, inflammatory signaling, and metabolic pathway activity in models of steatohepatitis and related liver dysfunction.
- Endocrinology Research: GLP-3 (RT) is evaluated to characterize interactions among GLP-1, GIP, and glucagon receptor pathways. Investigations examine insulin-secretion dynamics, glucose counter-regulation, receptor cross-talk, metabolic-hormone signaling, concentration-response windows, and adaptive endocrine responses.
- Thermogenesis Research: GLP-3 (RT) is studied for glucagon-receptor-associated effects on energy expenditure and substrate utilization. Research parameters include thermogenic signaling, brown-adipose-tissue activity, lipid and carbohydrate oxidation, and the relative contribution of energy-intake and energy-expenditure pathways to adipose-tissue endpoints.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for GLP-3 (RT) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
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Description
GLP-3 (RT) is a triple-agonist peptide simultaneously activating GLP-1, GIP, and glucagon receptors. Early preclinical data show pronounced metabolic endpoint changes at higher doses. The glucagon component adds thermogenic signaling and hepatic lipid oxidation absent from dual-agonists.Chemical Information
CAS Number
2381089-83-2
Purity
99%+ HPLC Verified
Molecular Formula
C221H342N46O68
Molar Mass
4731.3263 g/mol
Form Factor
Lyophilized Powder
Synonyms
Research Applications
- Metabolic Research: GLP-3 (RT) is investigated as a triple GLP-1, GIP, and glucagon receptor agonist in experimental metabolic models. Research focuses on adipose-tissue responses, multi-receptor signaling interactions, energy-balance regulation, and concentration-response relationships relative to single- and dual-receptor agonists.
- Hepatology Research: The glucagon-receptor activity of GLP-3 (RT) is studied for its influence on hepatic lipid oxidation and liver-fat metabolism. Experimental endpoints include hepatic lipid accumulation, fibrosis-associated markers, inflammatory signaling, and metabolic pathway activity in models of steatohepatitis and related liver dysfunction.
- Endocrinology Research: GLP-3 (RT) is evaluated to characterize interactions among GLP-1, GIP, and glucagon receptor pathways. Investigations examine insulin-secretion dynamics, glucose counter-regulation, receptor cross-talk, metabolic-hormone signaling, concentration-response windows, and adaptive endocrine responses.
- Thermogenesis Research: GLP-3 (RT) is studied for glucagon-receptor-associated effects on energy expenditure and substrate utilization. Research parameters include thermogenic signaling, brown-adipose-tissue activity, lipid and carbohydrate oxidation, and the relative contribution of energy-intake and energy-expenditure pathways to adipose-tissue endpoints.
Storage Conditions
Unreconstituted
Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.
Reconstituted
Refrigerate at 2–8°C. Use within 30 days for optimal stability.
Avoid
Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.
Safety & Compliance
- Wear nitrile gloves and safety goggles when handling research compounds.
- Work in a clean, controlled environment (laminar flow hood recommended).
- Dispose of sharps and used materials in approved biohazard containers.
- This product is for laboratory research use only (RUO) — not for human or veterinary use.
Quality Assurance Standards
Each production lot is subjected to rigorous analytical evaluation to meet pharmaceutical-grade specifications. Full testing results and procedural documentation are furnished through the accompanying Certificate of Analysis (COA) with every shipment.
Certificate of Analysis
Latest COA for GLP-3 (RT) — independently tested via HPLC and Mass Spectrometry.
Testing Methodology
Every batch undergoes a multi-stage analytical pipeline before release. Results are compiled into the Certificate of Analysis (COA) included with each order.
- • HPLC — High-Performance Liquid Chromatography confirms peptide purity ≥98%.
- • Mass Spectrometry — Validates molecular identity and correct sequence.
- • Endotoxin (LAL) — Limulus Amebocyte Lysate assay ensures endotoxin levels are within safe limits.
- • Sterility — Microbial contamination testing per USP standards.
Learn More About Peptides
Explore our research library covering purity, synthesis, storage, solubility, and more.
Research Database
Browse peer-reviewed studies, clinical trials, and scientific sources behind our peptide resources.
